The esophagus-wrapped collagen stick is made from 100% beef cattle collagen and wrapped in esophagus, creating an all-natural treat. Home Range Pet Treats are an all-natural, single-ingredient product sourced from animals raised without the use of hormones, steroids, and other antibiotics. Derived from grass-fed animals that are raised without the use of steroids, hormones, and antibiotics, and contain no added artificial preservatives, colors, or flavors.